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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PHGDH
All Species:
28.18
Human Site:
S407
Identified Species:
44.29
UniProt:
O43175
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43175
NP_006614.2
533
56651
S407
A
G
L
N
V
T
T
S
H
S
P
A
A
P
G
Chimpanzee
Pan troglodytes
A5A6P1
533
56644
S407
A
G
L
N
V
T
T
S
H
S
P
A
A
P
G
Rhesus Macaque
Macaca mulatta
XP_001114128
533
56466
S407
A
G
L
D
V
T
T
S
H
S
P
A
A
P
G
Dog
Lupus familis
XP_849835
533
56527
S407
A
G
L
S
V
T
T
S
H
N
P
A
V
P
G
Cat
Felis silvestris
Mouse
Mus musculus
Q61753
533
56567
S407
A
G
L
N
V
T
T
S
H
N
P
G
V
P
G
Rat
Rattus norvegicus
O08651
533
56475
S407
A
G
L
N
V
T
T
S
H
S
P
G
V
P
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515318
533
55943
T407
A
G
L
N
V
T
A
T
H
S
P
A
C
P
S
Chicken
Gallus gallus
XP_422226
525
55022
T405
A
G
L
K
V
T
A
T
H
G
D
T
C
P
E
Frog
Xenopus laevis
NP_001091250
509
53841
S404
K
S
T
G
I
Q
V
S
S
Q
H
F
S
G
A
Zebra Danio
Brachydanio rerio
NP_955871
527
55379
D408
T
G
I
T
V
H
T
D
H
K
A
S
D
E
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609496
332
35216
Q227
E
T
L
A
K
C
K
Q
G
V
K
V
V
N
V
Honey Bee
Apis mellifera
XP_001121753
478
51893
A364
N
G
L
N
L
I
N
A
P
T
L
A
Q
E
I
Nematode Worm
Caenorhab. elegans
NP_496868
322
34673
N218
K
Q
T
E
N
L
I
N
K
E
T
L
A
K
C
Sea Urchin
Strong. purpuratus
XP_001203904
493
51557
N372
L
G
L
E
I
T
V
N
N
E
D
A
A
P
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O04130
624
66436
N512
Q
I
L
N
V
E
S
N
F
A
G
A
V
S
D
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
98.8
92.5
N.A.
94.5
94.1
N.A.
82.5
67.5
56.2
60.7
N.A.
35
45
32.6
46.3
Protein Similarity:
100
99.6
99.2
96
N.A.
97
97.1
N.A.
90.2
80.1
71.6
75.9
N.A.
48.2
61.9
45.5
61.5
P-Site Identity:
100
100
93.3
80
N.A.
80
86.6
N.A.
73.3
46.6
6.6
26.6
N.A.
6.6
26.6
6.6
40
P-Site Similarity:
100
100
100
93.3
N.A.
86.6
86.6
N.A.
80
53.3
20
40
N.A.
6.6
46.6
13.3
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
33.1
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
48.5
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
46.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
54
0
0
7
0
0
14
7
0
7
7
54
34
0
14
% A
% Cys:
0
0
0
0
0
7
0
0
0
0
0
0
14
0
7
% C
% Asp:
0
0
0
7
0
0
0
7
0
0
14
0
7
0
7
% D
% Glu:
7
0
0
14
0
7
0
0
0
14
0
0
0
14
7
% E
% Phe:
0
0
0
0
0
0
0
0
7
0
0
7
0
0
0
% F
% Gly:
0
74
0
7
0
0
0
0
7
7
7
14
0
7
40
% G
% His:
0
0
0
0
0
7
0
0
60
0
7
0
0
0
0
% H
% Ile:
0
7
7
0
14
7
7
0
0
0
0
0
0
0
7
% I
% Lys:
14
0
0
7
7
0
7
0
7
7
7
0
0
7
0
% K
% Leu:
7
0
80
0
7
7
0
0
0
0
7
7
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
7
0
0
47
7
0
7
20
7
14
0
0
0
7
0
% N
% Pro:
0
0
0
0
0
0
0
0
7
0
47
0
0
60
0
% P
% Gln:
7
7
0
0
0
7
0
7
0
7
0
0
7
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% R
% Ser:
0
7
0
7
0
0
7
47
7
34
0
7
7
7
7
% S
% Thr:
7
7
14
7
0
60
47
14
0
7
7
7
0
0
0
% T
% Val:
0
0
0
0
67
0
14
0
0
7
0
7
34
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _